[Study of interaction of polystirolsulphonate with polymerization degree of 8 and polyallylamin with bilayer lipids membranes].
Identifieur interne : 002D87 ( Main/Exploration ); précédent : 002D86; suivant : 002D88[Study of interaction of polystirolsulphonate with polymerization degree of 8 and polyallylamin with bilayer lipids membranes].
Auteurs : S V Artiushenko ; N A Kontarov ; N V IuminovaSource :
- Biofizika [ 0006-3029 ]
Descripteurs français
- KwdFr :
- Double couche lipidique (), Inactivation virale, Polyamines (), Polystyrènes (), Protéines virales (), Protéines virales (métabolisme), Sous-type H2N2 du virus de la grippe A (), Sous-type H2N2 du virus de la grippe A (métabolisme), Virus de la rougeole (), Virus de la rougeole (métabolisme), Virus des oreillons (), Virus des oreillons (métabolisme).
- MESH :
English descriptors
- KwdEn :
- Influenza A Virus, H2N2 Subtype (chemistry), Influenza A Virus, H2N2 Subtype (metabolism), Lipid Bilayers (chemistry), Measles virus (chemistry), Measles virus (metabolism), Mumps virus (chemistry), Mumps virus (metabolism), Polyamines (chemistry), Polystyrenes (chemistry), Viral Proteins (chemistry), Viral Proteins (metabolism), Virus Inactivation.
- MESH :
- chemical , chemistry : Lipid Bilayers, Polyamines, Polystyrenes, Viral Proteins.
- chemistry : Influenza A Virus, H2N2 Subtype, Measles virus, Mumps virus.
- metabolism : Influenza A Virus, H2N2 Subtype, Measles virus, Mumps virus, Viral Proteins.
- Virus Inactivation.
Abstract
Interaction of polystirolsulphonate with polymerization degree of 8 (PSS-8) and polyallylamin PAA (molecular mass 60 kilodaltons) with viruses from bloodline of paramixo- and orthomixoviruses by the example of measles virus, parotitis and flu leads to the decreasing of infective activity. The possible mechanism of viral inhibitive action of these chemical compounds is damaging of interfacial antigenic proteins of paramixo- and orthomixoviruses. In this study it was detected the change of surface tension of bilayer lipid membrane in the presence of PSS-8 and PAA. The change of surface tension leads to disorder in viral proteins adsorption in bilayer lipid membrane. This process could lead to disorder of juncture and self-assembly of virions.
PubMed: 22594283
Affiliations:
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Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">[Study of interaction of polystirolsulphonate with polymerization degree of 8 and polyallylamin with bilayer lipids membranes].</title><author><name sortKey="Artiushenko, S V" sort="Artiushenko, S V" uniqKey="Artiushenko S" first="S V" last="Artiushenko">S V Artiushenko</name></author><author><name sortKey="Kontarov, N A" sort="Kontarov, N A" uniqKey="Kontarov N" first="N A" last="Kontarov">N A Kontarov</name></author><author><name sortKey="Iuminova, N V" sort="Iuminova, N V" uniqKey="Iuminova N" first="N V" last="Iuminova">N V Iuminova</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="????"><PubDate><MedlineDate>2012 Mar-Apr</MedlineDate></PubDate></date><idno type="RBID">pubmed:22594283</idno><idno type="pmid">22594283</idno><idno type="wicri:Area/PubMed/Corpus">000145</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000145</idno><idno type="wicri:Area/PubMed/Curation">000145</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000145</idno><idno type="wicri:Area/PubMed/Checkpoint">000592</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000592</idno><idno type="wicri:Area/Ncbi/Merge">000766</idno><idno type="wicri:Area/Ncbi/Curation">000766</idno><idno type="wicri:Area/Ncbi/Checkpoint">000766</idno><idno type="wicri:doubleKey">0006-3029::Artiushenko S:study:of:interaction</idno><idno type="wicri:Area/Main/Merge">002F62</idno><idno type="wicri:Area/Main/Curation">002D87</idno><idno type="wicri:Area/Main/Exploration">002D87</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Study of interaction of polystirolsulphonate with polymerization degree of 8 and polyallylamin with bilayer lipids membranes].</title><author><name sortKey="Artiushenko, S V" sort="Artiushenko, S V" uniqKey="Artiushenko S" first="S V" last="Artiushenko">S V Artiushenko</name></author><author><name sortKey="Kontarov, N A" sort="Kontarov, N A" uniqKey="Kontarov N" first="N A" last="Kontarov">N A Kontarov</name></author><author><name sortKey="Iuminova, N V" sort="Iuminova, N V" uniqKey="Iuminova N" first="N V" last="Iuminova">N V Iuminova</name></author></analytic><series><title level="j">Biofizika</title><idno type="ISSN">0006-3029</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Influenza A Virus, H2N2 Subtype (chemistry)</term><term>Influenza A Virus, H2N2 Subtype (metabolism)</term><term>Lipid Bilayers (chemistry)</term><term>Measles virus (chemistry)</term><term>Measles virus (metabolism)</term><term>Mumps virus (chemistry)</term><term>Mumps virus (metabolism)</term><term>Polyamines (chemistry)</term><term>Polystyrenes (chemistry)</term><term>Viral Proteins (chemistry)</term><term>Viral Proteins (metabolism)</term><term>Virus Inactivation</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Double couche lipidique ()</term><term>Inactivation virale</term><term>Polyamines ()</term><term>Polystyrènes ()</term><term>Protéines virales ()</term><term>Protéines virales (métabolisme)</term><term>Sous-type H2N2 du virus de la grippe A ()</term><term>Sous-type H2N2 du virus de la grippe A (métabolisme)</term><term>Virus de la rougeole ()</term><term>Virus de la rougeole (métabolisme)</term><term>Virus des oreillons ()</term><term>Virus des oreillons (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Lipid Bilayers</term><term>Polyamines</term><term>Polystyrenes</term><term>Viral Proteins</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Influenza A Virus, H2N2 Subtype</term><term>Measles virus</term><term>Mumps virus</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Influenza A Virus, H2N2 Subtype</term><term>Measles virus</term><term>Mumps virus</term><term>Viral Proteins</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Protéines virales</term><term>Sous-type H2N2 du virus de la grippe A</term><term>Virus de la rougeole</term><term>Virus des oreillons</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Virus Inactivation</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Double couche lipidique</term><term>Inactivation virale</term><term>Polyamines</term><term>Polystyrènes</term><term>Protéines virales</term><term>Sous-type H2N2 du virus de la grippe A</term><term>Virus de la rougeole</term><term>Virus des oreillons</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Interaction of polystirolsulphonate with polymerization degree of 8 (PSS-8) and polyallylamin PAA (molecular mass 60 kilodaltons) with viruses from bloodline of paramixo- and orthomixoviruses by the example of measles virus, parotitis and flu leads to the decreasing of infective activity. The possible mechanism of viral inhibitive action of these chemical compounds is damaging of interfacial antigenic proteins of paramixo- and orthomixoviruses. In this study it was detected the change of surface tension of bilayer lipid membrane in the presence of PSS-8 and PAA. The change of surface tension leads to disorder in viral proteins adsorption in bilayer lipid membrane. This process could lead to disorder of juncture and self-assembly of virions.</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Artiushenko, S V" sort="Artiushenko, S V" uniqKey="Artiushenko S" first="S V" last="Artiushenko">S V Artiushenko</name><name sortKey="Iuminova, N V" sort="Iuminova, N V" uniqKey="Iuminova N" first="N V" last="Iuminova">N V Iuminova</name><name sortKey="Kontarov, N A" sort="Kontarov, N A" uniqKey="Kontarov N" first="N A" last="Kontarov">N A Kontarov</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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